Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | F13A1 | P00488 | 1/20 | 0.49 |
| ▸ | VHL | P40337 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12133623 | 0.84 | KMT2A (0.76) | KMT2AHDAC1HDAC6HDAC2HDAC3 | |
| SCHEMBL4123487 | 0.82 | SMN1; SMN2 (0.56) | KMT2AMAPTALDH1A1POLBRAB9A | |
| SCHEMBL3612557 | 0.80 | KMT2A (0.66) | KMT2AHDAC1HDAC6HDAC2HDAC3 | |
| SCHEMBL171709 | 0.80 | KMT2A (0.66) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL24847549 | 0.78 | CYP1A2 (0.54) | KMT2AALDH1A1RAB9ASMN1; SMN2GAA | |
| SCHEMBL1653407 | 0.78 | CYP1A2 (0.54) | KMT2AALDH1A1RAB9ASMN1; SMN2GAA | |
| SCHEMBL97001 | 0.78 | KMT2A (0.68) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL1916981 | 0.78 | KMT2A (0.62) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL5210398 | 0.77 | KMT2A (0.67) | KMT2AHDAC1HDAC6HDAC2HDAC3 | |
| SCHEMBL19234514 | 0.77 | KMT2A (0.61) | KMT2AHDAC1HDAC6HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067522-A1 | AZAPHENYLALANINE DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | LEK PHARMACEUTICALS D.D. (SI) | 2004-08-12 | — | — | WO | disclosed |