Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 3/20 | 0.42 |
| ▸ | PNLIP | P16233 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | TYR | P14679 | 2/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 4/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826531 | 0.81 | KDM4E (0.46) | STK17BPNLIPKCNA3CSF1RKDR | |
| SCHEMBL6826534 | 0.81 | KDM4E (0.46) | STK17BPNLIPKCNA3CSF1RKDR | |
| SCHEMBL6824998 | 0.77 | STK17B (0.40) | STK17BPNLIPKCNA3 | |
| SCHEMBL6826162 | 0.76 | STK17B (0.37) | STK17BPNLIPKCNA3CSF1RKDR | |
| SCHEMBL6824994 | 0.76 | STK17B (0.40) | STK17BPNLIPKCNA3CSF1RKDR | |
| SCHEMBL6820565 | 0.75 | KCNA3 (0.36) | STK17BPNLIPKCNA3CSF1RKDR | |
| SCHEMBL6823667 | 0.74 | KCNA3 (0.37) | STK17BPNLIPKCNA3CSF1RKDR | |
| SCHEMBL6820553 | 0.74 | TYR (0.55) | STK17BPNLIPABCC2MAOBTYR | |
| SCHEMBL6820563 | 0.72 | KCNA3 (0.39) | STK17BPNLIPKCNA3CSF1RKDR | |
| SCHEMBL6824996 | 0.71 | STK17B (0.36) | STK17BPNLIPKCNA3MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | disclosed |