SCHEMBL6823822

SCHEMBL6823822

CN1CCC(Oc2cc(NS(=O)(=O)c3ccc(Sc4c(Cl)cccc4Cl)cc3Cl)ccc2C(F)(F)F)C1

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 18/20 0.62
P2RY4 P51582 1/20 0.38
PPARG P37231 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6820379 1.00 UTS2R (0.62) UTS2RP2RY4PPARG
SCHEMBL6820371 0.94 UTS2R (0.61) UTS2RPPARG
SCHEMBL6820360 0.94 UTS2R (0.61) UTS2RPPARG
SCHEMBL6820332 0.91 UTS2R (0.62) UTS2RP2RY4
SCHEMBL6820324 0.91 UTS2R (0.62) UTS2RP2RY4
SCHEMBL6822447 0.91 UTS2R (0.65) UTS2R
SCHEMBL6822449 0.91 UTS2R (0.65) UTS2R
SCHEMBL6821285 0.91 UTS2R (0.61) UTS2RPPARG
SCHEMBL6821277 0.91 UTS2R (0.61) UTS2RPPARG
SCHEMBL6817637 0.90 UTS2R (0.63) UTS2RPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043917-A1 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed