Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918243 | 0.88 | CCNA2 (0.39) | CDK2CCNA2CCNA1CYP1A2MAPT | |
| SCHEMBL6341505 | 0.81 | CCNA2 (0.43) | CDK2CCNA2CCNA1CYP1A2MAPT | |
| SCHEMBL6335444 | 0.81 | CCNA2 (0.39) | CDK2CCNA2CCNA1CYP1A2MAPT | |
| SCHEMBL6826896 | 0.78 | CCNA2 (0.45) | CDK2CCNA2CCNA1CYP1A2MAPT | |
| SCHEMBL6344162 | 0.78 | CCNA2 (0.39) | CDK2CCNA2CCNA1CYP1A2MAPT | |
| SCHEMBL6826015 | 0.77 | CCNA2 (0.40) | CDK2CCNA2CCNA1CYP1A2MAPT | |
| SCHEMBL6828252 | 0.76 | CCNA2 (0.40) | CDK2CCNA2CCNA1CYP1A2MAPT | |
| SCHEMBL5321153 | 0.75 | CCNA2 (0.39) | CDK2CCNA2CCNA1CYP1A2MAPT | |
| SCHEMBL6403920 | 0.75 | CCNA2 (0.37) | CDK2CCNA2CCNA1 | |
| SCHEMBL6335208 | 0.74 | MEN1 (0.40) | CDK2CCNA2CCNA1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004111000-A2 | PIPERIDYL DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS | ASTELLAS PHARMA INC. (JP) | 2004-12-23 | — | — | WO | disclosed |