Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 0.73 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827520 | 0.89 | NPY5R (0.66) | NPY5RGAAALDH1A1KDM4ECREBBP | |
| SCHEMBL6827663 | 0.88 | NPY5R (0.67) | NPY5RGAATSHRALDH1A1KDM4E | |
| SCHEMBL6826732 | 0.85 | NPY5R (1.00) | NPY5RTSHRALDH1A1KDM4ECYP2C9 | |
| SCHEMBL29434775 | 0.85 | NPY5R (1.00) | NPY5RTSHRALDH1A1KDM4ECYP2C9 | |
| SCHEMBL6826741 | 0.82 | NPY5R (0.65) | NPY5RGAAALDH1A1KDM4E | |
| SCHEMBL6826755 | 0.81 | NPY5R (0.64) | NPY5RGAAALDH1A1KDM4E | |
| SCHEMBL6826947 | 0.81 | NPY5R (0.62) | NPY5RGAAALDH1A1KDM4E | |
| SCHEMBL6829275 | 0.79 | NPY5R (0.69) | NPY5RREV1TSHRALDH1A1 | |
| SCHEMBL6826795 | 0.77 | NPY5R (0.58) | NPY5RALDH1A1L3MBTL1CYP2C19 | |
| SCHEMBL6827398 | 0.75 | NPY5R (0.55) | NPY5RGAATSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067999-A1 | Carbazole derivatives and their use as neuropeptide y5 receptor ligands | ASTRAZENECA AB (SE) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067999-A1 | Carbazole derivatives and their use as neuropeptide y5 receptor ligands | NPY5R, NPY1R, NPY2R | NPY5R 1/4885REV1 4218/4885GAA 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.