Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | SDCBP | O00560 | 1/20 | 0.36 |
| ▸ | SDC2 | P34741 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26654282 | 1.00 | MME (0.47) | MMEACECPA1ACE2TP53 | |
| SCHEMBL14115514 | 0.81 | PSEN1 (0.34) | MMEACECPA1ACE2 | |
| SCHEMBL4572623 | 0.80 | MME (0.50) | MMEACECPA1ACE2TP53 | |
| SCHEMBL6374397 | 0.80 | MME (0.50) | MMEACECPA1ACE2TP53 | |
| SCHEMBL15697685 | 0.78 | MME (0.48) | MMEACECPA1ACE2LTA4H | |
| SCHEMBL30628694 | 0.78 | MME (0.53) | MMEACECPA1ACE2LTA4H | |
| SCHEMBL19088373 | 0.77 | HIF1A (0.48) | — | |
| SCHEMBL12545610 | 0.77 | CA12 (0.39) | TP53LMNAFAAH | |
| SCHEMBL19000044 | 0.77 | CA12 (0.39) | TP53LMNAFAAH | |
| SCHEMBL19000042 | 0.77 | CA12 (0.39) | TP53LMNAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1496400-A | Process and microorganism for the preparation of 3- (2-hydroxy-3-methyl-butyrylamino) -propionic acid (HMBPA) | 巴斯福股份公司 | 2004-05-12 | — | — | CN | claimed |
| WO-2023223057-A1 | MACROCYCLIC COMPOUNDS AND USES THEREOF | CYPRALIS LIMITED (GB) | 2023-11-23 | — | — | WO | disclosed |
| CN-102690231-B | Method for synthesizing potential drug of Semagacestat for treating Alzheimer disease | NANJING YOUJIE MEDICAL TECHNOLOGY CO LTD | 2014-07-09 | — | — | CN | disclosed |
| CN-102690231-A | Method for synthesizing potential drug of Semagacestat for treating Alzheimer disease | NANJING YOUJIE MEDICAL TECHNOLOGY CO LTD | 2012-09-26 | — | — | CN | disclosed |
| EP-1377662-A2 | METHODS AND MICROORGANISMS FOR THE PRODUCTION OF 3-(2-HYDROXY-3-METHYL-BUTYRYLAMINO)-PROPIONIC ACID (HMBPA) | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002057476-A9 | METHODS AND MICROORGANISMS FOR THE PRODUCTION OF 3-(2-HYDROXY-3-METHYL-BUTYRYLAMINO)-PROPIONIC ACID (HMBPA) | OMNIGENE BIOPRODUCTS INC (US) | 2003-04-10 | — | — | WO | disclosed |
| WO-2002057476-A2 | METHODS AND MICROORGANISMS FOR THE PRODUCTION OF 3-(2-HYDROXY-3-METHYL-BUTYRYLAMINO)-PROPIONIC ACID (HMBPA) | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-25 | — | — | WO | disclosed |