Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 19/20 | 0.83 |
| ▸ | CDK2 | P24941 | 19/20 | 0.83 |
| ▸ | CCNE2 | O96020 | 16/20 | 0.83 |
| ▸ | CCNA2 | P20248 | 16/20 | 0.83 |
| ▸ | CCNA1 | P78396 | 16/20 | 0.83 |
| ▸ | CDK1 | P06493 | 1/20 | 0.74 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.73 |
| ▸ | CDK7 | P50613 | 1/20 | 0.73 |
| ▸ | CDK9 | P50750 | 1/20 | 0.73 |
| ▸ | CCNH | P51946 | 1/20 | 0.73 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.73 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6821075 | 0.99 | CCNE1 (0.82) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| SCHEMBL6820601 | 0.90 | CCNE2 (0.73) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| SCHEMBL6820605 | 0.90 | CCNE2 (0.73) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| SCHEMBL6821200 | 0.89 | CCNE2 (0.90) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| SCHEMBL6821203 | 0.89 | CCNE2 (0.90) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL6822214 | 0.89 | CCNE2 (0.72) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL6821698 | 0.89 | CCNE2 (0.72) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL6824017 | 0.88 | CCNE2 (0.88) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL6820812 | 0.88 | CCNE2 (0.88) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL6820813 | 0.88 | CCNE2 (0.88) | CCNE1CDK2CCNE2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056745-B1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMA INC (US) | 2004-06-16 | — | — | EP | claimed |