Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.58 |
| ▸ | CCNE1 | P24864 | 18/20 | 0.55 |
| ▸ | CDK2 | P24941 | 18/20 | 0.55 |
| ▸ | CDK1 | P06493 | 2/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.55 |
| ▸ | CCNE2 | O96020 | 16/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 14/20 | 0.55 |
| ▸ | CCNA1 | P78396 | 14/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.51 |
| ▸ | CDK9 | P50750 | 2/20 | 0.51 |
| ▸ | CDK7 | P50613 | 1/20 | 0.51 |
| ▸ | CCNH | P51946 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.51 |
| ▸ | CCNT2 | O60583 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824057 | 1.00 | FLT3 (0.58) | FLT3CCNE1CDK2CDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL6817986 | 0.99 | FLT3 (0.57) | FLT3CCNE1CDK2CDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL6817990 | 0.99 | FLT3 (0.57) | FLT3CCNE1CDK2CDK1CCNB1 | |
| SCHEMBL6824348 | 0.82 | CDK2 (0.60) | FLT3CCNE1CDK2CDK1CCNB1 | |
| SCHEMBL6824344 | 0.82 | CDK2 (0.60) | FLT3CCNE1CDK2CDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL6824011 | 0.81 | CDK2 (0.59) | FLT3CCNE1CDK2CDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL6817837 | 0.81 | CDK2 (0.59) | FLT3CCNE1CDK2CDK1CCNB1 | |
| SCHEMBL6824064 | 0.81 | CCNE1 (0.55) | CCNE1CDK2CDK1 | |
| Hydrochloric Acid SCHEMBL6817993 | 0.81 | CCNE1 (0.54) | CCNE1CDK2CDK1 | |
| SCHEMBL6820744 | 0.79 | CDK2 (0.59) | FLT3CCNE1CDK2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056745-B1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMA INC (US) | 2004-06-16 | — | — | EP | claimed |