Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 19/20 | 0.52 |
| ▸ | PDE4A | P27815 | 14/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817523 | 1.00 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL7114306 | 1.00 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL6197797 | 0.88 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL6196611 | 0.88 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL6196613 | 0.88 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL6820943 | 0.88 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6821339 | 0.88 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7119643 | 0.88 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7117812 | 0.88 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6823874 | 0.88 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051172-B1 | METHOD FOR TREATING COPD | SMITHKLINE BEECHAM CORP (US) | 2004-12-22 | — | — | EP | claimed |
| EP-0919544-B1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORP (US) | 2003-05-14 | — | — | EP | claimed |