Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.64 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.64 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 0.64 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.61 |
| ▸ | FAP | Q12884 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824148 | 1.00 | DPP4 (0.64) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL16578291 | 1.00 | DPP4 (0.64) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL16710010 | 1.00 | DPP4 (0.64) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL5649501 | 0.98 | DPP4 (0.66) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL355114 | 0.98 | DPP4 (0.66) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL297708 | 0.98 | DPP4 (0.66) | DPP4DPP8DPP9DPP7FAP | |
| Hydrochloric Acid SCHEMBL27616477 | 0.96 | DPP4 (0.64) | DPP4DPP8DPP9DPP7FAP | |
| Trifluoroacetic Acid SCHEMBL6923872 | 0.87 | DPP4 (0.67) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL3628073 | 0.82 | DPP4 (0.60) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL5966905 | 0.82 | DPP4 (0.60) | DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076434-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | claimed |
| WO-2004076433-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | claimed |
| WO-2004076434-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | disclosed |