SCHEMBL6824253

SCHEMBL6824253

Clc1ccc2ccccc2c1.[Zn]

nearest known ligand 0.94

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 7/20 0.94
MAPT P10636 2/20 0.50
LMNA P02545 2/20 0.50
HTT P42858 1/20 0.50
NR4A2 P43354 1/20 0.46
CYP1A2 P05177 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP3A4 P08684 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
MEN1 O00255 2/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
KMT2A Q03164 2/20 0.44
ALOX12 P18054 1/20 0.44
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL152521 0.97 CYP2A6 (1.00) CYP2A6MAPTLMNAHTTNR4A2
SCHEMBL30071035 0.97 CYP2A6 (1.00) CYP2A6MAPTLMNAHTTNR4A2
SCHEMBL8873844 0.97 CYP2A6 (1.00) CYP2A6MAPTLMNAHTTNR4A2
SCHEMBL29843547 0.97 CYP2A6 (1.00) CYP2A6MAPTLMNAHTTNR4A2
Methane SCHEMBL27919221 0.92 CYP2A6 (0.90) CYP2A6MAPTLMNAHTTNR4A2
Chlorobenzene SCHEMBL20479175 0.90 CYP2A6 (0.85) CYP2A6MAPTLMNAHTTNR4A2
SCHEMBL1359615 0.89 CYP2A6 (0.84) CYP2A6MAPTLMNAHTTNR4A2
SCHEMBL30413044 0.89 CYP2A6 (0.84) CYP2A6MAPTLMNAHTTNR4A2
SCHEMBL5052178 0.89 CYP2A6 (0.84) CYP2A6MAPTLMNAHTTNR4A2
SCHEMBL5464508 0.89 CYP2A6 (0.84) CYP2A6MAPTLMNAHTTNR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004050624-A1 SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES C & C RESEARCH LABORATORIES (KR) 2004-06-17 WO disclosed