SCHEMBL6824460

SCHEMBL6824460

COc1cccc(Sc2ccc(S(=O)(=O)Nc3ccc(C(F)(F)F)c(O[C@@H]4CCN(C)C4)c3)c(Cl)c2)c1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6824468 1.00 UTS2R (0.64) UTS2R
SCHEMBL6821277 0.91 UTS2R (0.61) UTS2R
SCHEMBL6821285 0.91 UTS2R (0.61) UTS2R
SCHEMBL6823993 0.91 UTS2R (0.64) UTS2R
SCHEMBL6823983 0.91 UTS2R (0.64) UTS2R
SCHEMBL6820376 0.90 UTS2R (0.71) UTS2R
SCHEMBL6820363 0.90 UTS2R (0.71) UTS2R
SCHEMBL6822449 0.90 UTS2R (0.65) UTS2R
SCHEMBL6822447 0.90 UTS2R (0.65) UTS2R
SCHEMBL6820379 0.89 UTS2R (0.62) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043917-A1 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed