Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 11/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824495 | 1.00 | ERN1 (0.64) | ERN1MAPTGAAKMT2AHPGD | |
| SCHEMBL29365000 | 0.82 | ERN1 (0.54) | ERN1MAPTGAAKMT2AHPGD | |
| SCHEMBL12858742 | 0.82 | ERN1 (0.54) | ERN1MAPTGAAKMT2AHPGD | |
| SCHEMBL16969061 | 0.79 | GAA (0.46) | ERN1MAPTGAAKMT2AHPGD | |
| SCHEMBL16969062 | 0.79 | GAA (0.46) | ERN1MAPTGAAKMT2AHPGD | |
| SCHEMBL881403 | 0.78 | ERN1 (1.00) | ERN1MAPT | |
| SCHEMBL29956082 | 0.78 | ERN1 (1.00) | ERN1MAPT | |
| SCHEMBL14922836 | 0.77 | MAPT (0.43) | ERN1MAPTGAAKMT2AHPGD | |
| SCHEMBL8942958 | 0.77 | MAPT (0.43) | ERN1MAPTGAAKMT2AHPGD | |
| SCHEMBL8942952 | 0.77 | MAPT (0.43) | ERN1MAPTGAAKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067518-A1 | SUBSTITUTED PYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-08-12 | — | — | WO | disclosed |