Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL6824583

NC(=O)C[C@H](N)C(=O)N1CCCC1.O=C(O)C(F)(F)F

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 14/20 0.44
DPP7 Q9UHL4 9/20 0.44
DPP9 Q86TI2 2/20 0.43
DPP4 P27487 7/20 0.43
PLAU P00749 1/20 0.38
PLAUR Q03405 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL6824630 0.89 DPP8 (0.43) DPP8DPP7DPP9DPP4
Trifluoroacetic Acid SCHEMBL6820631 0.83 DPP8 (0.44) DPP8DPP7DPP9DPP4PLAU
Trifluoroacetic Acid SCHEMBL6824636 0.82 DPP4 (0.45) DPP8DPP7DPP9DPP4
Trifluoroacetic Acid SCHEMBL6820639 0.82 DPP4 (0.45) DPP8DPP7DPP9DPP4
Trifluoroacetic Acid SCHEMBL6824315 0.81 DPP8 (0.48) DPP8DPP7DPP9DPP4
Trifluoroacetic Acid SCHEMBL6823789 0.79 DPP4 (0.49) DPP8DPP7DPP9DPP4
Trifluoroacetic Acid SCHEMBL6826281 0.79 DPP4 (0.49) DPP8DPP7DPP9DPP4
Trifluoroacetic Acid SCHEMBL6826242 0.78 DPP4 (0.48) DPP8DPP7DPP9DPP4
Trifluoroacetic Acid SCHEMBL6824018 0.77 DPP7 (0.51) DPP8DPP7DPP9DPP4
Trifluoroacetic Acid SCHEMBL6820916 0.77 DPP7 (0.54) DPP8DPP7DPP9DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004076433-A1 DIPEPTIDYL PEPTIDASE INHIBITORS AIC (BE) 2004-09-10 WO disclosed