SCHEMBL682469

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL683162	0.97	ESR1 (0.40)	ESR1PDE4APDE4BPDE4CPDE4D
	SCHEMBL6185088	0.96	ESR1 (0.42)	ESR1PDE4APDE4BPDE4CPDE4D
	Bromide SCHEMBL7526402	0.95	ESR1 (0.41)	ESR1PDE4APDE4BPDE4CPDE4D
	SCHEMBL17678230	0.81	ESR1 (0.40)	ESR1
	SCHEMBL3167730	0.81	PDE4A (0.41)	ESR1PDE4APDE4BPDE4CPDE4D
	SCHEMBL3602527	0.80	PDE4A (0.39)	ESR1PDE4APDE4BPDE4CPDE4D
	SCHEMBL6179851	0.80	KHK (0.32)	KHK
	SCHEMBL2144178	0.80	MAPK1 (0.39)	PDE4APDE4BPDE4CPDE4DKHK
	SCHEMBL6796557	0.80	PTGDR2 (0.47)	ESR1PDE4APDE4BPDE4CPDE4D
	SCHEMBL6182637	0.79	ESR1 (0.40)	ESR1PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.