Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5994823 | 0.92 | MAPT (0.47) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL5995294 | 0.87 | TP53 (0.44) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL5996138 | 0.84 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL5994346 | 0.82 | ABCG2 (0.46) | TP53ABCG2MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL5996392 | 0.80 | ABCG2 (0.45) | TP53ABCG2MAPTKMT2AMEN1 | |
| SCHEMBL5997265 | 0.79 | ABCG2 (0.46) | TP53ABCG2MAPTKMT2AMEN1 | |
| SCHEMBL5995330 | 0.78 | CYP3A4 (0.40) | TP53ABCG2MAPTKMT2AMEN1 | |
| SCHEMBL5996921 | 0.78 | ABCG2 (0.40) | TP53ABCG2MAPTKMT2AMEN1 | |
| SCHEMBL14519861 | 0.78 | NPC1 (0.60) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL5997937 | 0.77 | ABCG2 (0.45) | TP53ABCG2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737549-B2 | PHOTOINITIATORS FOR ACRYLATE COATINGS | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-05-18 | — | — | US | disclosed |
| US-20020026049-A1 | Photoinitiators for acrylate coatings | CIBA SPECIALTY CHEMICALS CORP. | 2002-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020026049-A1 | Photoinitiators for acrylate coatings | DHCR24, NR5A1, NR2C2 | PDE4A 4298/4885PDE4B 4454/4885PDE4C 3908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.