Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.43 |
| ▸ | XIAP | P98170 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6829199 | 0.91 | ADORA2A (0.44) | ADORA2AADORA1XIAPMAPTHTT | |
| Hydrochloric Acid SCHEMBL6924932 | 0.91 | ADORA2A (0.44) | ADORA2AADORA1XIAPMAPTHTT | |
| Hydrochloric Acid SCHEMBL6133657 | 0.91 | ADORA2A (0.44) | ADORA2AADORA1XIAPMAPTHTT | |
| Hydrochloric Acid SCHEMBL6134333 | 0.89 | ADORA2A (0.43) | ADORA2AADORA1XIAPMAPTHTT | |
| SCHEMBL6133951 | 0.89 | ADORA2A (0.45) | ADORA2AADORA1XIAPMAPTHTT | |
| SCHEMBL6134810 | 0.87 | ADORA2A (0.47) | ADORA2AADORA1XIAPMAPTHTT | |
| Hydrochloric Acid SCHEMBL6134092 | 0.86 | ADORA2A (0.43) | ADORA2AADORA1XIAPMAPTHTT | |
| Hydrochloric Acid SCHEMBL6133730 | 0.86 | ADORA2A (0.46) | ADORA2AADORA1XIAPMAPTHTT | |
| SCHEMBL6133306 | 0.85 | ADORA1 (0.60) | ADORA2AADORA1XIAPMAPTHTT | |
| SCHEMBL6133361 | 0.85 | ADORA2A (0.48) | ADORA2AADORA1XIAPMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441732-A2 | THIAZOLE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003039451-A2 | THIAZOLE PYRIDAZINONES AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-15 | — | — | WO | disclosed |