⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1057906 | 0.81 | — | — | |
| SCHEMBL1057742 | 0.81 | — | — | |
| SCHEMBL6137576 | 0.79 | — | — | |
| SCHEMBL1058031 | 0.79 | — | — | |
| SCHEMBL16218833 | 0.71 | — | — | |
| SCHEMBL14952932 | 0.70 | — | — | |
| SCHEMBL16209240 | 0.70 | — | — | |
| SCHEMBL18649592 | 0.70 | — | — | |
| SCHEMBL18029421 | 0.68 | MEN1 (0.35) | — | |
| SCHEMBL8649774 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439837-A1 | PYRAZOLIDINONE COMPOUNDS AS LIGANDS OF THE PROSTAGLANDIN EP2 AND/OR EP4 RECEPTORS | Applied Research Systems ARS Holding N.V. (AN) | 2004-07-28 | — | — | EP | disclosed |
| WO-2003035064-A1 | PYRAZOLIDINONE COMPOUNDS AS LIGANDS OF THE PROSTAGLANDIN EP2 AND/OR EP4 RECEPTORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-05-01 | — | — | WO | disclosed |