Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.68 |
| ▸ | ERBB2 | P04626 | 18/20 | 0.56 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6823449 | 0.99 | EGFR (0.68) | EGFRERBB2ERBB4 | |
| Hydrochloric Acid SCHEMBL6827548 | 0.88 | EGFR (0.84) | EGFRERBB2 | |
| SCHEMBL6487746 | 0.86 | EGFR (0.66) | EGFRERBB2ERBB4 | |
| SCHEMBL6487743 | 0.86 | EGFR (0.66) | EGFRERBB2ERBB4 | |
| SCHEMBL6826817 | 0.83 | EGFR (0.67) | EGFRERBB2ERBB4 | |
| SCHEMBL6826922 | 0.82 | EGFR (0.66) | EGFRERBB2ERBB4 | |
| SCHEMBL6826777 | 0.82 | EGFR (0.63) | EGFRERBB2ERBB4 | |
| SCHEMBL6823747 | 0.82 | EGFR (0.65) | EGFRERBB2ERBB4 | |
| Hydrochloric Acid SCHEMBL6827547 | 0.81 | EGFR (0.62) | EGFRERBB2ERBB4 | |
| SCHEMBL6826984 | 0.81 | EGFR (1.00) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004112714-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-29 | — | — | WO | claimed |
| WO-2004112714-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-29 | — | — | WO | disclosed |