Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MDM4 | O15151 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.49 |
| ▸ | IL1RN | P18510 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008631 | 1.00 | NPSR1 (0.53) | NPSR1KMT2ACNR1CNR2LNPEP | |
| SCHEMBL1721283 | 1.00 | NPSR1 (0.53) | NPSR1KMT2ACNR1CNR2LNPEP | |
| SCHEMBL31390194 | 0.91 | CNR1 (0.48) | NPSR1KMT2ACNR1CNR2LNPEP | |
| SCHEMBL8234170 | 0.90 | POLB (0.48) | TSHRPOLBCYP2C19ALDH1A1 | |
| SCHEMBL2252892 | 0.90 | FOLH1 (0.56) | TSHRESR1LMNACYP1A2CYP2D6 | |
| SCHEMBL2252894 | 0.90 | FOLH1 (0.56) | TSHRESR1LMNACYP1A2CYP2D6 | |
| SCHEMBL8019599 | 0.88 | POLB (0.47) | TSHRPOLB | |
| SCHEMBL8234657 | 0.88 | POLB (0.47) | TSHRPOLB | |
| SCHEMBL7495527 | 0.88 | TSHR (0.49) | LNPEPTSHRERAP2ERAP1POLB | |
| SCHEMBL842451 | 0.88 | CNR1 (0.52) | NPSR1KMT2ACNR1CNR2LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6740637-B1 | PHOTODYNAMIC THERAPY (PDT) PHOTOSENSITIZERS; TUMOR DIAGNOSIS; CONJUGATION WITH CELL-SPECIFIC LIGANDS, TARGET THE TUMOR SITE; MELANOCYTE STIMULATING HORMONES CONJUGATES ARE SUITABLE FOR PDT OF MELANOMA TUMORS | YEDA RESEARCH AND DEVELOPMENT CO. (IL) | 2004-05-25 | — | — | US | disclosed |