⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184838 | 1.00 | — | — | |
| SCHEMBL7123634 | 0.81 | — | — | |
| SCHEMBL28139368 | 0.81 | — | — | |
| SCHEMBL9484430 | 0.77 | — | — | |
| SCHEMBL7703784 | 0.76 | HSP90AA1 (0.35) | — | |
| SCHEMBL11876642 | 0.75 | — | — | |
| SCHEMBL84451 | 0.75 | — | — | |
| SCHEMBL29448509 | 0.75 | — | — | |
| SCHEMBL4263709 | 0.75 | — | — | |
| Water SCHEMBL8524004 | 0.73 | HSP90AA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132758-A1 | PESTICIDALLY ACTIVE QUINAZOLINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-06-26 | — | — | WO | disclosed |
| WO-2025132349-A1 | PESTICIDALLY ACTIVE QUINAZOLINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-06-26 | — | — | WO | disclosed |
| WO-2024099478-A1 | INHALABLE AROMATIC RING THIAZIDE AND ANALOG, PHARMACEUTICAL COMPOSITION CONTAINING INHALABLE AROMATIC RING THIAZINE, AND USE OF INHALABLE AROMATIC RING THIAZINE IN ANTI-INFLAMMATION AND ANTI-TUMOR | 杭州百诚医药科技股份有限公司 | 2024-05-16 | — | — | WO | disclosed |
| CN-117088867-A | Inhalable aromatic ring thiazide and analogue, pharmaceutical composition containing inhalable aromatic ring thiazide and analogue and application of inhalable aromatic ring thiazide and analogue in anti-inflammatory and anti-tumor | 杭州百诚医药科技股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| EP-4017590-A1 | PYRAZOLO[4,3-C]PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS | Galapagos N.V. (BE) | 2022-06-29 | — | — | EP | disclosed |
| CN-109906224-A | TRIAZOLOPYRIDINE COMPOUNDS AND USES THEREOF | 诺华股份有限公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-106456639-B | Prodrugs of HIV Reverse Transcriptase Inhibitors | 默沙东公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-109414415-A | The treatment of cutaneous lesions | 皮奎尔治疗公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-104822670-B | 5-phenoxy-3H-pyrimidin-4-one derivatives and their use as HIV reverse transcriptase inhibitors | 默沙东公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-107108644-A | Difluoromethyl aminopyridine and difluoromethyl aminopyrimidine | 皮奎尔治疗公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-106456639-A | Prodrugs of hiv reverse transcriptase inhibitors | 默沙东公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105473572-A | Herbicidal compounds | SYNGENTA LTD | 2016-04-06 | — | — | CN | disclosed |
| CN-104902751-A | Method for promoting plant growth | SUMITOMO CHEMICAL CO | 2015-09-09 | — | — | CN | disclosed |
| CN-104902750-A | Method for promoting plant growth | SUMITOMO CHEMICAL CO | 2015-09-09 | — | — | CN | disclosed |
| CN-104902752-A | Method for promoting plant growth | SUMITOMO CHEMICAL CO | 2015-09-09 | — | — | CN | disclosed |
| CN-104902749-A | Method for promoting plant growth | SUMITOMO CHEMICAL CO | 2015-09-09 | — | — | CN | disclosed |
| EP-2903977-A1 | 5-PHENOXY-3H-PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS HIV REVERSE TRANSCRIPTASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2015-08-12 | — | — | EP | disclosed |
| WO-2014058747-A1 | 5-PHENOXY-3H-PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS HIV REVERSE TRANSCRIPTASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-04-17 | — | — | WO | disclosed |
| CN-101384263-A | Is suitable for treating dopamine D3Triazole compounds for receptor-mediated diseases | ABBOTT GMBH & CO KG (DE) | 2009-03-11 | — | — | CN | disclosed |
| WO-2004108706-A1 | TRIAZOLE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR | ABBOTT GMBH & CO. KG (DE) | 2004-12-16 | — | — | WO | disclosed |