Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 13/20 | 0.73 |
| ▸ | TACR3 | P29371 | 2/20 | 0.61 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8792622 | 0.89 | DHODH (0.72) | DHODHTACR3PDE10ALMNATSHR | |
| SCHEMBL3908668 | 0.89 | DHODH (0.71) | DHODHTACR3PDE10ALMNAADORA2A | |
| SCHEMBL8794728 | 0.87 | DHODH (0.68) | DHODHTACR3 | |
| SCHEMBL8792497 | 0.86 | DHODH (0.60) | DHODHTACR3PDE10ALMNATSHR | |
| SCHEMBL8793224 | 0.85 | DHODH (0.58) | DHODHPDE10ALMNATSHRCYP2D6 | |
| SCHEMBL8792419 | 0.85 | DHODH (1.00) | DHODH | |
| SCHEMBL4666226 | 0.85 | DHODH (0.68) | DHODHTACR3PDE10ALMNAADORA2A | |
| SCHEMBL8794378 | 0.84 | DHODH (0.90) | DHODH | |
| SCHEMBL8794131 | 0.83 | DHODH (0.76) | DHODHTACR3PDE10ALMNATSHR | |
| SCHEMBL3902769 | 0.82 | TACR3 (0.61) | DHODHTACR3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050627-A1 | A QUINOLINE AMIDE DERIVATIVE AS AGENT AGAINST DISORDERS OF THE CNS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-17 | — | — | WO | disclosed |