SCHEMBL6826852

SCHEMBL6826852

CC(=O)C(C(=O)Nc1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.60
ATM Q13315 3/20 0.60
RAB9A P51151 3/20 0.60
HSP90AA1 P07900 2/20 0.60
NPC1 O15118 2/20 0.60
CYP1A2 P05177 1/20 0.59
CYP2C19 P33261 1/20 0.59
ALDH1A1 P00352 4/20 0.57
MAPT P10636 4/20 0.57
LMNA P02545 1/20 0.57
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
GPR55 Q9Y2T6 2/20 0.50
HPGD P15428 1/20 0.50
HTT P42858 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
HSD17B10 Q99714 1/20 0.50
POLB P06746 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL935298 0.87 CYP1A2 (0.68) GAAATMRAB9AHSP90AA1NPC1
SCHEMBL12957588 0.87 GAA (0.57) GAAATMRAB9AHSP90AA1NPC1
SCHEMBL27534883 0.86 GAA (0.64) GAAATMRAB9AHSP90AA1NPC1
SCHEMBL11452160 0.84 CYP1A2 (0.64) GAAATMRAB9AHSP90AA1NPC1
SCHEMBL1086017 0.82 GAA (0.64) GAAATMRAB9AHSP90AA1NPC1
SCHEMBL600051 0.81 TDP1 (0.52) ATMRAB9ANPC1CYP2C19ALDH1A1
SCHEMBL2853917 0.81 TDP1 (0.52) ATMRAB9ANPC1CYP2C19ALDH1A1
SCHEMBL28659721 0.79 CYP1A2 (0.59) GAAATMRAB9AHSP90AA1NPC1
SCHEMBL11607787 0.79 TDP1 (0.50) ATMRAB9ANPC1ALDH1A1MAPT
SCHEMBL29251170 0.79 TDP1 (0.50) ATMRAB9ANPC1CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0108023-B1 PROCESS FOR THE STABILIZATION OF VINYL CHLORIDE POLYMERS RHONE-POULENC CHIMIE (FR) 1986-12-17 EP claimed
EP-1337509-A4 POLYMERIC ACETOACETANILIDE AZO COLORANTS MILLIKEN & CO (US) 2004-05-19 EP disclosed
US-6667392-B2 Colorants having poly(oxyalkylene)chain exhibit extremely good base stability and lightfastness, particularly when incoporated within certain media and/or on surface of certain substrates MILLIKEN & COMPANY 2003-12-23 US disclosed
EP-1337509-A1 POLYMERIC ACETOACETANILIDE AZO COLORANTS Milliken & Company (US) 2003-08-27 EP disclosed
US-20020177640-A1 Polymeric acetoacetanilide azo colorants MILLIKEN & COMPANY 2002-11-28 US disclosed
WO-2002044134-A1 POLYMERIC ACETOACETANILIDE AZO COLORANTS MILLIKEN & COMPANY (US) 2002-06-06 WO disclosed
WO-1998022822-A9 PHOTOGRAPHIC COLOR COUPLERS USED AS CYTOCHEMICAL CONTRAST MARKERS 1998-09-11 WO disclosed
WO-1998022822-A1 PHOTOGRAPHIC COLOR COUPLERS USED AS CYTOCHEMICAL CONTRAST MARKERS APPLIED IMAGING CORPORATION (US) 1998-05-28 WO disclosed
US-4968824-A CROSSLINKING PROMOTER RHONE-POULENC CHIMIE (FR) 1990-11-06 US disclosed
US-4956436-A POLYSILOXANES WITH A CROSSLINKING AGENT AND A CATALYTIC ORGANOTIN COMPOUND RHONE-POULENC CHIMIE (FR) 1990-09-11 US disclosed
US-4954539-A CONTAINING DIHYDROXYDIORGANOPOLYSILOXANE, ORGANOHYDROPOLYSILOXANE, POLYVINYL ALCOHOL, NONIONIC EMULSIFIERS, TIN CROSSLINKING CATALYST RHONE-POULENC CHIMIE (FR) 1990-09-04 US disclosed
US-4873305-A CURABLE ELASTOMER; MOLDING MATERIAL RHONE-POULENC CHIMIE (FR) 1989-10-10 US disclosed
US-4267083-A ADDING AN ORGANOMETALLIC SALT, DIKETONE, AND SUBSTITUTED DIHYDROPYRIDINE RHONE-POULENC INDUSTRIES (FR) 1981-05-12 US disclosed