SCHEMBL682717

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2137756	1.00	PDE4D (0.41)	PDE4DPDE4BPDE4APDE4CNR1H2
	SCHEMBL683342	0.91	PDE4B (0.42)	PDE4DPDE4BPDE4APDE4CNR1H2
	SCHEMBL877637	0.91	PDE4B (0.42)	PDE4DPDE4BPDE4APDE4CNR1H2
	SCHEMBL876882	0.91	NR1H2 (0.40)	NR1H2NR1H3ALDH1A1DPP4
	SCHEMBL683355	0.91	NR1H2 (0.40)	NR1H2NR1H3ALDH1A1DPP4
	SCHEMBL876713	0.90	PDE4B (0.36)	PDE4DPDE4BPDE4APDE4CNR1H2
	SCHEMBL876712	0.90	PDE4B (0.36)	PDE4DPDE4BPDE4APDE4CNR1H2
	SCHEMBL878473	0.88	PDE4D (0.43)	PDE4DPDE4BPDE4APDE4C
	SCHEMBL681944	0.88	PDE4D (0.43)	PDE4DPDE4BPDE4APDE4C
	SCHEMBL682994	0.87	PDE4D (0.45)	PDE4DPDE4BPDE4APDE4CNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.