⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78215 | 1.00 | — | — | |
| SCHEMBL27807433 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1846071 | 0.97 | FFAR4 (0.46) | — | |
| SCHEMBL28222962 | 0.97 | FFAR4 (0.46) | — | |
| SCHEMBL7077832 | 0.97 | FFAR4 (0.46) | — | |
| SCHEMBL15092783 | 0.97 | FFAR4 (0.46) | — | |
| Methane SCHEMBL28811094 | 0.97 | FFAR4 (0.46) | — | |
| SCHEMBL30787402 | 0.94 | FFAR1 (0.56) | — | |
| SCHEMBL30787267 | 0.94 | FFAR1 (0.56) | — | |
| SCHEMBL30787135 | 0.94 | FFAR1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773869-B9 | MACROCYCLIC MODULATORS OF THE GHRELIN RECEPTOR | TRANZYME PHARMA INC (CA) | 2013-01-23 | — | — | EP | disclosed |
| EP-2287161-B1 | Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of CNS disorders | OTSUKA PHARMA CO LTD (JP) | 2012-05-09 | — | — | EP | disclosed |
| US-7198761-B2 | Vehicle hydrogen fuel system | DAIMLERCHRYSLER CORPORATION (US) | 2007-04-03 | — | — | US | disclosed |
| WO-2004111041-A1 | PYRROLIDINE, THIAZOLIDINE AND OXAZOLIDINE COMPOUNDS WHICH INHIBIT DIPEPTIDYL PEPTIDASE-IV (DPP) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-23 | — | — | WO | disclosed |