Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 17/20 | 0.50 |
| ▸ | CA9 | Q16790 | 17/20 | 0.50 |
| ▸ | CA1 | P00915 | 13/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824860 | 0.90 | CA12 (0.47) | CA12CA9CA1ALDH1A1MAPT | |
| SCHEMBL6824989 | 0.88 | CA12 (0.50) | CA12CA9CA1CA2 | |
| SCHEMBL6824978 | 0.86 | CA12 (0.48) | CA12CA9CA1CA2 | |
| SCHEMBL6824983 | 0.81 | CA12 (0.43) | CA12CA9CA1CA2 | |
| SCHEMBL6825234 | 0.81 | CA9 (0.66) | CA12CA9CA1ALDH1A1MAPT | |
| SCHEMBL6821696 | 0.77 | CA9 (0.64) | CA12CA9CA1SMN1; SMN2CA2 | |
| SCHEMBL6827172 | 0.77 | CA12 (0.63) | CA12CA9CA1ALDH1A1MAPT | |
| SCHEMBL6825144 | 0.76 | CA9 (0.72) | CA12CA9CA1ALDH1A1MAPT | |
| SCHEMBL6821697 | 0.74 | CA12 (0.61) | CA12CA9CA1ALDH1A1MAPT | |
| SCHEMBL6824885 | 0.72 | CA9 (0.62) | CA12CA9CA1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004099127-A1 | NOVEL COMPOUNDS AS KINASE INHIBITORS | NOVO NORDISK A/S (DK) | 2004-11-18 | — | — | WO | disclosed |