Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 19/20 | 0.67 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.67 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.67 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4712892 | 0.94 | MAPK8 (0.67) | MAPK8MAPK9MAPK10DPP4 | |
| SCHEMBL4713811 | 0.92 | MAPK8 (0.56) | MAPK8MAPK9MAPK10DPP4 | |
| SCHEMBL4709264 | 0.91 | MAPK8 (0.68) | MAPK8MAPK9MAPK10DPP4 | |
| SCHEMBL4713919 | 0.90 | MAPK8 (0.60) | MAPK8MAPK9MAPK10DPP4 | |
| SCHEMBL4709765 | 0.88 | MAPK8 (0.64) | MAPK8MAPK9MAPK10DPP4 | |
| SCHEMBL4710998 | 0.85 | MAPK8 (0.82) | MAPK8MAPK9MAPK10 | |
| SCHEMBL4710478 | 0.84 | MAPK8 (0.70) | MAPK8MAPK9MAPK10DPP4 | |
| SCHEMBL4711756 | 0.83 | MAPK8 (0.73) | MAPK8MAPK9MAPK10DPP4 | |
| SCHEMBL4709199 | 0.83 | MAPK8 (0.64) | MAPK8MAPK9MAPK10DPP4 | |
| SCHEMBL4711062 | 0.83 | MAPK8 (0.81) | MAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1484320-A1 | JNK INHIBITOR | Takeda Chemical Industries, Ltd. (JP) | 2004-12-08 | — | — | EP | disclosed |