SCHEMBL682796

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2142566	1.00	PDE4A (0.40)	PDE4APDE4BPDE4CPDE4DNR1H2
	SCHEMBL873476	0.95	NR1H2 (0.39)	NR1H2NR1H3MEN1APOBEC3AKMT2A
	SCHEMBL681914	0.95	NR1H2 (0.39)	NR1H2NR1H3MEN1APOBEC3AKMT2A
	SCHEMBL683404	0.93	PDE4D (0.49)	PDE4APDE4BPDE4CPDE4D
	SCHEMBL681920	0.93	PDE4D (0.47)	PDE4APDE4BPDE4CPDE4DNR1H2
	SCHEMBL2137979	0.93	PDE4D (0.49)	PDE4APDE4BPDE4CPDE4D
	SCHEMBL877588	0.93	PDE4D (0.47)	PDE4APDE4BPDE4CPDE4DNR1H2
	SCHEMBL2139161	0.92	PDE4A (0.42)	PDE4APDE4BPDE4CPDE4DNR1H2
	SCHEMBL683108	0.92	PDE4A (0.42)	PDE4APDE4BPDE4CPDE4DNR1H2
	SCHEMBL683118	0.91	PDE4D (0.49)	PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.