Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.93 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.93 |
| ▸ | MAPT | P10636 | 9/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.68 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.58 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.58 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935186 | 0.96 | MEN1 (1.00) | MEN1KMT2AMAPTLMNANPSR1 | |
| Benzene SCHEMBL27988126 | 0.96 | MEN1 (1.00) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL28213002 | 0.92 | MEN1 (0.84) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL14432387 | 0.91 | MEN1 (0.90) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL2411174 | 0.91 | MEN1 (0.90) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL27872595 | 0.91 | MEN1 (0.90) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL7273126 | 0.90 | KMT2A (0.87) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL9726815 | 0.90 | MEN1 (0.87) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL12913257 | 0.90 | KMT2A (0.87) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL9726818 | 0.90 | MEN1 (0.87) | MEN1KMT2AMAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076425-A1 | IMPROVED SYNTHESIS OF MACROCYCLIC TETRAAMIDO COMPOUNDS AND NEW METAL INSERTION PROCESS | CARNEGIE MELLON UNIVERSITY (US) | 2004-09-10 | — | — | WO | disclosed |