SCHEMBL6828141

SCHEMBL6828141

Cc1c(O)ccc2c1oc(=O)c1c(C)c(O)c(Cl)cc12

nearest known ligand 0.85

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 20/20 0.85
ESR1 P03372 16/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6828759 0.82 ESR2 (1.00) ESR2ESR1
SCHEMBL6828684 0.80 ESR1 (0.62) ESR2ESR1
SCHEMBL26768202 0.78 ESR2 (0.84) ESR2ESR1
SCHEMBL9211529 0.74 KDM4E (0.66) ESR2ESR1
SCHEMBL3766383 0.73 KDM4E (0.74) ESR2ESR1
SCHEMBL6828387 0.72 ESR2 (1.00) ESR2ESR1
SCHEMBL6926052 0.72 ESR2 (1.00) ESR2ESR1
SCHEMBL22413393 0.72 ESR2 (0.71) ESR2ESR1
SCHEMBL6828078 0.72 ESR2 (1.00) ESR2ESR1
SCHEMBL6825648 0.72 ESR2 (0.77) ESR2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004073612-A2 ESTROGEN RECEPTOR MODULATORS MERCK & CO. INC. (US) 2004-09-02 WO claimed