SCHEMBL6828223

SCHEMBL6828223

C=CC=CCC(O)CCCCC=CCCCC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.54
FFAR4 Q5NUL3 1/20 0.54
FAAH O00519 2/20 0.47
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
LTB4R Q15722 2/20 0.38
ALDH1A1 P00352 1/20 0.38
LTB4R2 Q9NPC1 1/20 0.38
EP300 Q09472 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
MEN1 O00255 1/20 0.37
CYP3A4 P08684 1/20 0.37
KMT2A Q03164 1/20 0.37
PPARG P37231 2/20 0.36
ABCG2 Q9UNQ0 1/20 0.36
CACNA2D1 P54289 1/20 0.36
CACNB2 Q08289 1/20 0.36
CACNA1C Q13936 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30853070 0.88 FFAR1 (0.50) FFAR1FFAR4FAAHNFKB1NFKB2
SCHEMBL30005487 0.88 FFAR1 (0.50) FFAR1FFAR4FAAHNFKB1NFKB2
SCHEMBL30853081 0.84 FFAR1 (0.46) FFAR1FFAR4FAAHNFKB1ALDH1A1
SCHEMBL28350184 0.83 FFAR1 (0.49) FFAR1FFAR4FAAHMEN1CYP3A4
SCHEMBL6904194 0.83 FFAR1 (0.49) FFAR1FFAR4FAAHMEN1CYP3A4
SCHEMBL29167955 0.83 FFAR1 (0.49) FFAR1FFAR4FAAHMEN1CYP3A4
SCHEMBL6589273 0.83 FFAR1 (0.45) FFAR1FFAR4FAAHALDH1A1MAPT
SCHEMBL5906871 0.83 FFAR1 (0.49) FFAR1FFAR4FAAHMEN1CYP3A4
SCHEMBL7171994 0.83 FFAR1 (0.49) FFAR1FFAR4FAAHMEN1CYP3A4
SCHEMBL29150766 0.83 FFAR1 (0.45) FFAR1FFAR4FAAHALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1417195-A1 CERTAIN SUBSTITUTED POLYKETIDES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN TREATING TUMORS Novartis AG (CH) 2004-05-12 EP disclosed
WO-2003014102-A1 CERTAIN SUBSTITUTED POLYKETIDES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN TREATING TUMORS NOVARTIS AG (CH) 2003-02-20 WO disclosed