Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.52 |
| ▸ | HRH1 | P35367 | 5/20 | 0.52 |
| ▸ | HTR2B | P41595 | 5/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6461468 | 1.00 | ACACB (0.55) | ACACBMCHR1ADRA2AHRH1HTR2B | |
| SCHEMBL6461475 | 1.00 | ACACB (0.55) | ACACBMCHR1ADRA2AHRH1HTR2B | |
| SCHEMBL6457553 | 0.91 | MCHR1 (0.63) | ACACBMCHR1ADRA2AHRH1HTR2B | |
| SCHEMBL6457562 | 0.91 | MCHR1 (0.63) | ACACBMCHR1ADRA2AHRH1HTR2B | |
| Hydrochloric Acid SCHEMBL6458543 | 0.90 | MCHR1 (0.62) | ACACBMCHR1ADRA2AHRH1HTR2B | |
| Hydrochloric Acid SCHEMBL6458533 | 0.90 | MCHR1 (0.62) | ACACBMCHR1ADRA2AHRH1HTR2B | |
| SCHEMBL6458805 | 0.90 | POLB (0.56) | ACACBMCHR1ADRA2AHRH1HTR2B | |
| SCHEMBL6457598 | 0.90 | POLB (0.56) | ACACBMCHR1ADRA2AHRH1HTR2B | |
| SCHEMBL6458800 | 0.90 | POLB (0.56) | ACACBMCHR1ADRA2AHRH1HTR2B | |
| SCHEMBL6457584 | 0.90 | POLB (0.56) | ACACBMCHR1ADRA2AHRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |