Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.75 |
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.75 |
| ▸ | FAP | Q12884 | 12/20 | 0.62 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.62 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3150545 | 1.00 | DPP4 (0.75) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL3155789 | 0.91 | DPP4 (0.63) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL3160876 | 0.90 | DPP4 (0.62) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL3165183 | 0.90 | DPP4 (0.62) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL3155999 | 0.90 | DPP4 (0.67) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL3165763 | 0.90 | DPP4 (0.64) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL3165068 | 0.90 | DPP4 (0.74) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL3160933 | 0.89 | DPP4 (0.64) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL3160605 | 0.89 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL3166137 | 0.89 | DPP4 (0.74) | DPP4DPP7FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092128-A1 | ANHYDROUS CRYSTALLINE FORMS OF (2S, 4S)-1-{(2R)-2-AMINO-3-‘4-METHOXYBENZYL)SULFONYL!-3-METHYLBUTANOYL}-4-FLUOROPYRROLINDINE-2-CARBONITRILE | SMITHKLINE BEECHAM CORPORATION (US) | 2004-10-28 | — | — | WO | disclosed |