Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ATF4 | P18848 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460438 | 0.89 | HPGD (0.57) | HTTHPGDRAB9ALMNASMN1; SMN2 | |
| SCHEMBL6460432 | 0.89 | HPGD (0.57) | HTTHPGDRAB9ALMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6458868 | 0.88 | HPGD (0.56) | HTTHPGDRAB9ALMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6458857 | 0.88 | HPGD (0.56) | HTTHPGDRAB9ALMNASMN1; SMN2 | |
| SCHEMBL6828732 | 0.85 | NOTUM (0.67) | HTTHPGDRAB9ALMNAKMT2A | |
| SCHEMBL6828725 | 0.85 | NOTUM (0.67) | HTTHPGDRAB9ALMNAKMT2A | |
| SCHEMBL6460127 | 0.85 | SMN1; SMN2 (0.62) | HTTHPGDRAB9ALMNASMN1; SMN2 | |
| SCHEMBL6462820 | 0.85 | HPGD (0.60) | HTTHPGDRAB9ALMNASMN1; SMN2 | |
| SCHEMBL6462809 | 0.85 | HPGD (0.60) | HTTHPGDRAB9ALMNASMN1; SMN2 | |
| SCHEMBL6460117 | 0.85 | SMN1; SMN2 (0.62) | HTTHPGDRAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |