Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 13/20 | 0.56 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SGK1 | O00141 | 1/20 | 0.37 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.36 |
| ▸ | USP1 | O94782 | 1/20 | 0.35 |
| ▸ | USP8 | P40818 | 1/20 | 0.35 |
| ▸ | OTUB1 | Q96FW1 | 1/20 | 0.35 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828739 | 1.00 | UTS2R (0.56) | UTS2RHTR6DRD2HTR2CDRD3 | |
| SCHEMBL8339640 | 0.91 | UTS2R (0.56) | UTS2RHTR6DRD2HTR2CDRD3 | |
| SCHEMBL6826100 | 0.91 | UTS2R (0.56) | UTS2RHTR6DRD2HTR2CPFKFB3 | |
| SCHEMBL6826097 | 0.91 | UTS2R (0.56) | UTS2RHTR6DRD2HTR2CPFKFB3 | |
| SCHEMBL6830219 | 0.90 | UTS2R (0.53) | UTS2RHTR6DRD2HTR2CDRD3 | |
| SCHEMBL6830221 | 0.90 | UTS2R (0.53) | UTS2RHTR6DRD2HTR2CDRD3 | |
| SCHEMBL6828657 | 0.90 | UTS2R (0.55) | UTS2RHTR6DRD2HTR2CDRD3 | |
| SCHEMBL6828655 | 0.90 | UTS2R (0.55) | UTS2RHTR6DRD2HTR2CDRD3 | |
| SCHEMBL6828702 | 0.89 | UTS2R (0.57) | UTS2RHTR6DRD2HTR2CDRD3 | |
| SCHEMBL6828704 | 0.89 | UTS2R (0.57) | UTS2RHTR6DRD2HTR2CDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043368-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043368-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |