Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 20/20 | 0.71 |
| ▸ | CHUK | O15111 | 11/20 | 0.71 |
| ▸ | CDK2 | P24941 | 1/20 | 0.55 |
| ▸ | BTK | Q06187 | 1/20 | 0.55 |
| ▸ | ITK | Q08881 | 1/20 | 0.55 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829023 | 0.91 | IKBKB (0.85) | IKBKBCHUKCDK2BTKITK | |
| SCHEMBL5660578 | 0.85 | IKBKB (0.68) | IKBKBCHUK | |
| SCHEMBL5656141 | 0.83 | IKBKB (1.00) | IKBKBCHUKCDK2BTKITK | |
| SCHEMBL14589438 | 0.82 | IKBKB (1.00) | IKBKBCHUKCDK2BTKITK | |
| SCHEMBL14589449 | 0.82 | IKBKB (0.72) | IKBKBCHUKCDK2BTKITK | |
| SCHEMBL14589443 | 0.81 | IKBKB (0.90) | IKBKBCHUKCDK2BTKITK | |
| SCHEMBL14589450 | 0.78 | IKBKB (0.66) | IKBKBCHUK | |
| SCHEMBL14589455 | 0.78 | IKBKB (0.77) | IKBKBCHUK | |
| SCHEMBL14589494 | 0.77 | IKBKB (0.73) | IKBKBCHUKCDK2BTKITK | |
| SCHEMBL14589440 | 0.77 | IKBKB (1.00) | IKBKBCHUKCDK2BTKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106293-A2 | OXAZOLYL - AND THIAZOLYL - PURINE BASED TRICYCLIC COMPOUNDS. | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-09 | — | — | WO | claimed |