⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL603726 | 0.76 | — | — | |
| SCHEMBL6548267 | 0.76 | — | — | |
| SCHEMBL11661888 | 0.70 | — | — | |
| SCHEMBL6548807 | 0.67 | — | — | |
| SCHEMBL47793 | 0.67 | — | — | |
| SCHEMBL419784 | 0.67 | — | — | |
| SCHEMBL1591040 | 0.67 | — | — | |
| SCHEMBL823853 | 0.60 | — | — | |
| SCHEMBL6957444 | 0.56 | — | — | |
| SCHEMBL3749197 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116724-A1 | Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds | KINNEY WILLIAM A (US) | 2004-06-17 | — | — | US | disclosed |
| EP-1389623-A2 | Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin d analogs, and other compounds | MAGAININ PHARMACEUTICALS INC. (US) | 2004-02-18 | — | — | EP | disclosed |
| US-6610866-B2 | Reacting unsaturated alkyl ketone with chiral oxazaborolidine compound to form unsaturated alkyl alcohol; intermediates for production of squalamine | MAGAININ PHARMACEUTICALS, INC. | 2003-08-26 | — | — | US | disclosed |
| US-20020068834-A1 | Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds | MAGAININ PHARMACEUTICALS, INC. | 2002-06-06 | — | — | US | disclosed |
| US-6262283-B1 | SULFATION | MAGAININ PHARMACEUTICALS INC. | 2001-07-17 | — | — | US | disclosed |
| EP-0942918-A2 | STEREOSELECTIVE SYNTHESIS OF 24-HYDROXYLATED COMPOUNDS USEFUL FOR THE PREPARATION OF AMINOSTEROLS, VITAMIN D ANALOGS, AND OTHER COMPOUNDS | MAGAININ PHARMACEUTICALS INC. (US) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998024800-A2 | STEREOSELECTIVE SYNTHESIS OF 24-HYDROXYLATED COMPOUNDS USEFUL FOR THE PREPARATION OF AMINOSTEROLS, VITAMIN D ANALOGS, AND OTHER COMPOUNDS | MAGAININ PHARMACEUTICALS INC. (US) | 1998-06-11 | — | — | WO | disclosed |