SCHEMBL682891

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL875241	1.00	KHK (0.39)	KHKADRB1PDE4APDE4BPDE4C
	Hydrochloric Acid SCHEMBL874611	0.99	KHK (0.38)	KHKADRB1PDE4APDE4BPDE4C
	SCHEMBL873409	0.94	ABCB1 (0.39)	KHKADRB1PRKCAPRKCQPRKCD
	SCHEMBL2138093	0.94	ABCB1 (0.39)	KHKADRB1PRKCAPRKCQPRKCD
	SCHEMBL2138371	0.92	PDE4A (0.46)	KHKPDE4APDE4BPDE4CPDE4D
	SCHEMBL682874	0.92	PDE4D (0.48)	PDE4APDE4BPDE4CPDE4DPOLB
	SCHEMBL681792	0.92	PDE4A (0.46)	KHKPDE4APDE4BPDE4CPDE4D
	SCHEMBL2139736	0.92	PDE4D (0.48)	PDE4APDE4BPDE4CPDE4DPOLB
	Hydrochloric Acid SCHEMBL875394	0.91	PDE4D (0.47)	PDE4APDE4BPDE4CPDE4DPOLB
	Hydrochloric Acid SCHEMBL2139482	0.91	PDE4D (0.47)	PDE4APDE4BPDE4CPDE4DPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.