Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 11/20 | 0.53 |
| ▸ | KDR | P35968 | 9/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826990 | 0.95 | SRC (0.52) | SRCKDRFGFR1SYK | |
| SCHEMBL16742203 | 0.89 | TSHR (0.46) | SRCKDRHRH3MAPK1ALDH1A1 | |
| SCHEMBL3203162 | 0.84 | SRC (0.43) | SRCKDRALDH1A1 | |
| SCHEMBL16742200 | 0.83 | SRC (0.53) | SRCKDRHRH3FGFR1 | |
| SCHEMBL16747710 | 0.82 | PIK3CD (0.43) | SRCHRH3MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL3204677 | 0.81 | KDR (0.55) | SRCKDRSIGMAR1 | |
| SCHEMBL16742355 | 0.80 | HRH3 (0.42) | SRCHRH3MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL6829060 | 0.80 | SRC (0.69) | SRCKDR | |
| SCHEMBL18128960 | 0.79 | SRC (0.56) | SRCKDRFGFR1 | |
| SCHEMBL4292544 | 0.79 | KDM4E (0.37) | SRCKDRSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108707-A1 | PYRIDAZINIL QUINAZOLINE DERIVATIVES FOR USE IN THE TREATMENT OF TUMOURS | ASTRAZENECA AB (SE) | 2004-12-16 | — | — | WO | disclosed |