Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.84 |
| ▸ | ERBB2 | P04626 | 11/20 | 0.65 |
| ▸ | GAK | O14976 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826984 | 0.92 | EGFR (1.00) | EGFRERBB2GAK | |
| SCHEMBL6826956 | 0.89 | EGFR (0.83) | EGFRERBB2GAK | |
| SCHEMBL6826817 | 0.89 | EGFR (0.67) | EGFRERBB2 | |
| SCHEMBL6827596 | 0.88 | EGFR (0.82) | EGFRERBB2 | |
| SCHEMBL6483980 | 0.87 | EGFR (0.78) | EGFRERBB2GAK | |
| SCHEMBL6483295 | 0.87 | EGFR (0.80) | EGFRERBB2GAK | |
| SCHEMBL6487865 | 0.86 | EGFR (0.80) | EGFRERBB2GAK | |
| SCHEMBL4587900 | 0.85 | EGFR (1.00) | EGFRERBB2GAK | |
| SCHEMBL6483126 | 0.84 | EGFR (0.79) | EGFRERBB2GAK | |
| SCHEMBL6488644 | 0.84 | EGFR (0.77) | EGFRERBB2GAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004112714-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-29 | — | — | WO | disclosed |