SCHEMBL6829331

SCHEMBL6829331

Oc1ccccc1C1CCCN1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.47
CHRM5 P08912 5/20 0.44
CHRM3 P20309 5/20 0.44
CHRM2 P08172 5/20 0.44
CHRM1 P11229 4/20 0.44
CHRM4 P08173 4/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CHRNB2 P17787 1/20 0.43
CHRNA7 P36544 1/20 0.43
CHRNA4 P43681 1/20 0.43
IKBKB O14920 1/20 0.43
CDK5 Q00535 1/20 0.42
CDK5R1 Q15078 1/20 0.42
TAAR1 Q96RJ0 1/20 0.40
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10653671 0.94 IKBKB (0.48) DRD2CHRM5CHRM3CHRM2CHRM1
SCHEMBL13928040 0.81 MEN1 (0.39) DRD2MEN1KMT2AIKBKB
SCHEMBL23323069 0.78 CHRM5 (0.46) CHRM5CHRM3CHRM2CHRM1CHRM4
SCHEMBL22165432 0.78 CHRM5 (0.46) CHRM5CHRM3CHRM2CHRM1CHRM4
SCHEMBL22165430 0.78 CHRM5 (0.46) CHRM5CHRM3CHRM2CHRM1CHRM4
SCHEMBL29747061 0.78 CHRM5 (0.46) CHRM5CHRM3CHRM2CHRM1CHRM4
SCHEMBL29589068 0.78 CHRM5 (0.46) CHRM5CHRM3CHRM2CHRM1CHRM4
SCHEMBL22423673 0.77 CHRM5 (0.44) CHRM5CHRM3CHRM2CHRM1CHRM4
SCHEMBL24737035 0.77 CHRM5 (0.44) CHRM5CHRM3CHRM2CHRM1CHRM4
SCHEMBL23323100 0.77 HTR2C (0.52) CHRM5CHRM3CHRM2CHRM1CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110156813-B Heterocyclic compounds as TRK inhibitors 北京诺诚健华医药科技有限公司 2023-07-25 CN disclosed
US-6740326-B1 WATER-FREE TOPICAL APPLICATION COMPOSITION FOR TREATMENT OF NAIL DISEASES AND NAIL CARE CONSISTING OF ANTIMYCOTIC AGENT AND LOWER ALKYL ESTER OF LACTIC ACID, MALIC ACID, TARTARIC ACID OR CITRIC ACID AS PENETRATION PROMOTING CARRIER BIOEQUAL AG (CH) 2004-05-25 US disclosed
CN-1169736-A Catalyst for olefin polymerization ASAHI CHEMICAL IND (JP) 1998-01-07 CN disclosed