Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3622346 | 0.81 | CYP19A1 (0.43) | CYP19A1 | |
| SCHEMBL3622348 | 0.81 | CYP19A1 (0.43) | CYP19A1 | |
| SCHEMBL6997314 | 0.80 | CYP2D6 (0.42) | KCNN4ALDH1A1MAPT | |
| SCHEMBL26688903 | 0.77 | CUL4A (0.33) | CUL4ACYP19A1KDM4ELOXL2ALDH1A1 | |
| SCHEMBL10369991 | 0.74 | ESR1 (0.44) | KCNN4CYP17A1KDM4EALDH1A1MAPT | |
| SCHEMBL28801791 | 0.74 | KCNN4 (0.38) | KCNN4CYP17A1CUL4ACYP19A1ALDH1A1 | |
| SCHEMBL4463031 | 0.73 | KCNN4 (0.40) | KCNN4CUL4ACYP19A1KDM4ELOXL2 | |
| SCHEMBL7908310 | 0.73 | KCNN4 (0.40) | KCNN4CYP17A1KDM4ELOXL2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27898355 | 0.72 | KCNN4 (0.36) | KCNN4CYP17A1CUL4AALDH1A1MAPT | |
| Methylene Chloride SCHEMBL27898354 | 0.72 | ESR1 (0.35) | KCNN4CUL4ALOXL2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058727-A1 | SUBSTITUTED 3,5-DIHYDRO-4H-IMIDAZOL-4-ONES FOR THE TREATMENT OF OBESITY | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |