Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL7736841 | 0.97 | ITGB1 (0.79) | ITGB1ITGA4 | |
| SCHEMBL6629174 | 0.91 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL6627364 | 0.90 | ITGB1 (0.73) | ITGB1ITGA4 | |
| SCHEMBL6626315 | 0.89 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL6823871 | 0.88 | ITGB1 (1.00) | ITGB1ITGA4 | |
| Alcohol SCHEMBL7742085 | 0.86 | ITGB1 (0.95) | ITGB1ITGA4 | |
| SCHEMBL6582297 | 0.83 | ITGB1 (0.86) | ITGB1ITGA4 | |
| SCHEMBL6827904 | 0.83 | ITGB1 (0.86) | ITGB1ITGA4 | |
| SCHEMBL6827303 | 0.83 | ITGB1 (0.72) | ITGB1ITGA4 | |
| SCHEMBL6629973 | 0.83 | ITGB1 (0.82) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1154987-B1 | PHENYLALANINOL DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2004-04-21 | — | — | EP | claimed |
| EP-1154987-A1 | PHENYLALANINOL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-21 | — | — | EP | claimed |
| WO-2000048988-A1 | PHENYLALANINOL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-08-24 | — | — | WO | claimed |
| EP-1154987-B1 | PHENYLALANINOL DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2004-04-21 | — | — | EP | disclosed |
| US-6420600-B1 | HYDROXYALKYLPHENYLDIAMIDES | HOFFMAN-LA ROCHE INC. | 2002-07-16 | — | — | US | disclosed |
| EP-1154987-A1 | PHENYLALANINOL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000048988-A1 | PHENYLALANINOL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-08-24 | — | — | WO | disclosed |