SCHEMBL683017

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL878073	1.00	FNTA (0.43)	FNTAFNTBS1PR1CYP3A4CYP2D6
	SCHEMBL682679	0.89	PDE4B (0.43)	FNTAFNTBS1PR1CYP3A4CYP2D6
	SCHEMBL876730	0.89	PDE4B (0.43)	FNTAFNTBS1PR1CYP3A4CYP2D6
	SCHEMBL2141438	0.89	S1PR1 (0.43)	FNTAFNTBS1PR1CYP3A4CYP2D6
	SCHEMBL882600	0.89	S1PR1 (0.43)	FNTAFNTBS1PR1CYP3A4CYP2D6
	SCHEMBL877189	0.87	NR1H2 (0.39)	FNTAFNTBNR1H2NR1H3CCR5
	SCHEMBL877190	0.87	NR1H2 (0.39)	FNTAFNTBNR1H2NR1H3CCR5
	SCHEMBL683023	0.85	NR1H2 (0.43)	NR1H2NR1H3CCR5TRPC6ABCB1
	SCHEMBL2138237	0.85	NR1H2 (0.43)	NR1H2NR1H3CCR5TRPC6ABCB1
	SCHEMBL873399	0.84	NR1H2 (0.44)	NR1H2NR1H3CCR5ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.