Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Flunisolide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 known ✓ | P04150 | 6/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.98 |
| ▸ | PGR | P06401 | 7/20 | 0.98 |
| ▸ | LMNA | P02545 | 6/20 | 0.98 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.98 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.98 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.98 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.98 |
| ▸ | HTR1A | P08908 | 1/20 | 0.98 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.98 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.98 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.69 |
| ▸ | AR | P10275 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flunisolide SCHEMBL22527648 | 1.00 | CYP3A4 (0.98) | CYP3A4PGRNR3C1LMNAABCB11 | |
| Flunisolide SCHEMBL76502 | 1.00 | CYP3A4 (0.98) | CYP3A4PGRNR3C1LMNAABCB11 | |
| Flunisolide SCHEMBL4351 | 0.99 | CYP3A4 (1.00) | CYP3A4PGRNR3C1LMNAABCB11 | |
| Flunisolide SCHEMBL13026142 | 0.99 | CYP3A4 (1.00) | CYP3A4PGRNR3C1LMNAABCB11 | |
| Flunisolide SCHEMBL5493687 | 0.99 | CYP3A4 (1.00) | CYP3A4PGRNR3C1LMNAABCB11 | |
| Flunisolide SCHEMBL8810954 | 0.99 | CYP3A4 (1.00) | CYP3A4PGRNR3C1LMNAABCB11 | |
| Flunisolide SCHEMBL66051 | 0.99 | CYP3A4 (1.00) | CYP3A4PGRNR3C1LMNAABCB11 | |
| Flunisolide SCHEMBL5187487 | 0.99 | CYP3A4 (1.00) | CYP3A4PGRNR3C1LMNAABCB11 | |
| Flunisolide SCHEMBL13662143 | 0.99 | CYP3A4 (1.00) | CYP3A4PGRNR3C1LMNAABCB11 | |
| Flunisolide SCHEMBL30994800 | 0.99 | CYP3A4 (1.00) | CYP3A4PGRNR3C1LMNAABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040011061-A1 | Device and process for the cryogenic filling of aerosol product batches | BITZ ANDRE (DE) | 2004-01-22 | — | — | US | claimed |
| CN-122029166-A | Condensed cyclic compound and harmful arthropod control composition containing the same | 住友化学株式会社 | 2026-05-12 | — | — | CN | disclosed |
| CN-115484825-B | Phenyl compound and method for controlling plant disease | 住友化学株式会社 | 2025-06-24 | — | — | CN | disclosed |
| CN-120019050-A | Sulfonamide compound and harmful arthropod control composition containing same | 住友化学株式会社 | 2025-05-16 | — | — | CN | disclosed |
| CN-119997815-A | Dry formulations of active ingredients | FMC公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-119998283-A | Sulfonamide compound and harmful arthropod control composition containing same | 住友化学株式会社 | 2025-05-13 | — | — | CN | disclosed |
| CN-119947587-A | Phenylpyrazole compound and method for controlling plant disease | 住友化学株式会社 | 2025-05-06 | — | — | CN | disclosed |
| CN-119948026-A | Heterocyclic compound and harmful arthropod control composition containing same | 住友化学株式会社 | 2025-05-06 | — | — | CN | disclosed |
| CN-119451572-A | Method for controlling plant disease | 住友化学株式会社 | 2025-02-14 | — | — | CN | disclosed |
| CN-118104671-B | Synergistic compound composition containing amide insecticide and application thereof | 沈阳中化农药化工研发有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-117412966-A | Condensed pyridines for combating invertebrate pests | FMC公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-116634871-A | Pesticidal compounds and compositions, methods of use and methods of preparation thereof | 阿达玛马克西姆有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116456817-A | Heterocyclic compound and harmful arthropod control composition containing same | 住友化学株式会社 | 2023-07-18 | — | — | CN | disclosed |
| CN-116249449-A | Compositions and methods for preparing N-phenylpyrazole-1-carboxamides | FMC公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-116234811-A | Pesticidally active heterocyclic derivatives with sulfur containing substituents | 先正达农作物保护股份公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116056577-A | Pesticidally active heterocyclic derivatives with sulfur containing substituents | 先正达农作物保护股份公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-116018344-A | Pesticidally active heterocyclic derivatives with sulfur containing substituents | 先正达农作物保护股份公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-115996640-A | Chromeneone compounds for controlling invertebrate pests | FMC公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115003666-A | Pesticidally active fused bicyclic heteroaromatic amino compounds | 先正达农作物保护股份公司 | 2022-09-02 | — | — | CN | disclosed |
| US-20040011061-A1 | Device and process for the cryogenic filling of aerosol product batches | BITZ ANDRE (DE) | 2004-01-22 | — | — | US | disclosed |