Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 11/20 | 0.70 |
| ▸ | MAPK9 | P45984 | 10/20 | 0.70 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ILK | Q13418 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026702 | 0.89 | MAPK10 (0.88) | MAPK10MAPK9MAPK8HPGDALOX5 | |
| SCHEMBL1518642 | 0.83 | MAPK10 (1.00) | MAPK10MAPK9MAPK8HPGDALOX5 | |
| SCHEMBL5596240 | 0.82 | MAPK10 (0.78) | MAPK10MAPK9MAPK8HPGDHSD17B10 | |
| SCHEMBL5975967 | 0.80 | MAPK10 (0.69) | MAPK10MAPK9MAPK8HPGDHSD17B10 | |
| SCHEMBL5102944 | 0.80 | MAPK10 (0.74) | MAPK10MAPK9MAPK8HPGDHSD17B10 | |
| SCHEMBL4023709 | 0.80 | MAPK10 (0.78) | MAPK10MAPK9MAPK8ALOX5MEN1 | |
| SCHEMBL4020889 | 0.79 | MAPK10 (0.77) | MAPK10MAPK9MAPK8ALOX5ILK | |
| SCHEMBL4022971 | 0.78 | MAPK10 (0.84) | MAPK10MAPK9MAPK8CYP1A2CYP2C9 | |
| SCHEMBL4020743 | 0.78 | MAPK10 (0.81) | MAPK10MAPK9MAPK8ALOX5ILK | |
| SCHEMBL2886417 | 0.78 | MAPK10 (0.81) | MAPK10MAPK9MAPK8ALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450792-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF SCLERODERMA | Applied Research Systems ARS Holding N.V. (AN) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003047570-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF SCLERODERMA | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2003-06-12 | — | — | WO | disclosed |