SCHEMBL6830661

SCHEMBL6830661

COc1ccc(-c2cc(S(=O)(=O)Nc3ccc(C(F)(F)F)c(OC4CCN(C)C4)c3)sc2Cl)cc1

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 18/20 0.59
FFAR4 Q5NUL3 1/20 0.39
PLAU P00749 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6830659 1.00 UTS2R (0.59) UTS2RFFAR4PLAU
SCHEMBL6828891 0.93 UTS2R (0.57) UTS2RFFAR4
SCHEMBL6828887 0.93 UTS2R (0.57) UTS2RFFAR4
SCHEMBL6826061 0.92 UTS2R (0.57) UTS2R
SCHEMBL6830487 0.92 UTS2R (0.57) UTS2R
SCHEMBL6826059 0.92 UTS2R (0.57) UTS2R
SCHEMBL6830485 0.92 UTS2R (0.57) UTS2R
SCHEMBL6829911 0.92 UTS2R (0.57) UTS2R
SCHEMBL6829906 0.92 UTS2R (0.57) UTS2R
SCHEMBL6828350 0.91 UTS2R (0.56) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043368-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO claimed
WO-2004043368-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed