Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830934 | 1.00 | ESR1 (0.50) | ESR1CYP19A1CYP11B2AKR1C1PTGS2 | |
| SCHEMBL420328 | 0.98 | ESR1 (0.53) | ESR1CYP19A1CYP11B2AKR1C1PTGS2 | |
| SCHEMBL420327 | 0.90 | ESR1 (0.46) | ESR1CYP19A1CYP11B2AKR1C1PTGS2 | |
| SCHEMBL420330 | 0.83 | CYP19A1 (0.39) | ESR1CYP19A1CYP11B2AKR1C1PTGS2 | |
| SCHEMBL11315161 | 0.82 | MAPT (0.59) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL55433 | 0.79 | ESR1 (0.74) | ESR1CYP19A1CYP11B2AKR1C1PTGS2 | |
| SCHEMBL3851043 | 0.77 | AKR1C1 (0.48) | ESR1CYP19A1CYP11B2AKR1C1PRMT1 | |
| SCHEMBL3851044 | 0.77 | AKR1C1 (0.48) | ESR1CYP19A1CYP11B2AKR1C1PRMT1 | |
| SCHEMBL30366689 | 0.77 | ESR1 (0.71) | ESR1CYP19A1CYP11B2AKR1C1PTGS2 | |
| Phosphine SCHEMBL28461311 | 0.77 | ESR1 (0.71) | ESR1CYP19A1CYP11B2AKR1C1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1489891-A1 | COLOR EMISSION DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2004-12-22 | — | — | EP | disclosed |