SCHEMBL683096

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL876647	1.00	NR1H2 (0.44)	NR1H2NR1H3CHRM4ABCB1TRPC6
	SCHEMBL877178	0.90	PDE4B (0.42)	NR1H2NR1H3
	SCHEMBL877179	0.90	PDE4B (0.42)	NR1H2NR1H3
	SCHEMBL683396	0.90	NR1H2 (0.46)	NR1H2NR1H3CHRM4ABCB1TRPC6
	SCHEMBL2139740	0.90	NR1H2 (0.46)	NR1H2NR1H3CHRM4ABCB1TRPC6
	SCHEMBL682652	0.85	NR1H2 (0.47)	NR1H2NR1H3CHRM4ABCB1TRPC6
	SCHEMBL876732	0.85	NR1H2 (0.47)	NR1H2NR1H3CHRM4ABCB1TRPC6
	SCHEMBL682038	0.83	PDE4B (0.48)	NR1H2NR1H3
	SCHEMBL2141419	0.83	PDE4B (0.50)	NR1H2NR1H3
	SCHEMBL2140386	0.83	PDE4B (0.48)	NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.