Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 14/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ELOVL1 | Q9BW60 | 4/20 | 0.37 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830971 | 1.00 | NPY5R (0.59) | NPY5RDRD3ELOVL1DEGS1 | |
| SCHEMBL4714625 | 0.87 | NPY5R (0.66) | NPY5RDRD3ELOVL1 | |
| SCHEMBL4714629 | 0.87 | NPY5R (0.66) | NPY5RDRD3ELOVL1 | |
| SCHEMBL4712593 | 0.79 | NPY5R (0.72) | NPY5RDRD3 | |
| SCHEMBL4712597 | 0.79 | NPY5R (0.72) | NPY5RDRD3 | |
| SCHEMBL2658975 | 0.75 | NPY5R (0.71) | NPY5RDRD3 | |
| SCHEMBL2658977 | 0.75 | NPY5R (0.71) | NPY5RDRD3 | |
| SCHEMBL2660138 | 0.75 | NPY5R (1.00) | NPY5RDRD3 | |
| SCHEMBL2660140 | 0.75 | NPY5R (1.00) | NPY5RDRD3 | |
| SCHEMBL4713991 | 0.74 | NPY5R (0.69) | NPY5RDRD3ELOVL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6803372-B2 | SUCH AS CIS-N-(4-BENZOYLPHENYL)-4-HYDROXY-3'-OXOSPIRO (CYCLOHEXANE-1,1' (3'H)-ISOBENZOFURAN)-4-CARBOXAMIDE FOR USE AS NEUROPEPTIDE Y RECEPTOR ANTAGONIST FOR TREATMENT BULIMIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-10-12 | — | — | US | claimed |